Coronation Street cast members Brooke Vincent (Sophie Webster), Ryan Thomas (Jason Grimshaw), Sue Cleaver (Eileen Grimshaw) and Ben Price (Nick Tilsley) are involved.
It's on ITV1 tonight, Friday 17 August, at 9pm.
There's pics and a video online so you can have a sneak peek at what will be shown in tonight's documentary.
The documentary was filmed with the actors helping out with a charity called S.A.F.E. and their goal is to raise awareness about HIV.
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